Norcholic Acid

CAS No. 60696-62-0

Norcholic Acid( —— )

Catalog No. M34922 CAS No. 60696-62-0

Norcholic Acid (Nor Cholic Acid) is a bile acid that promotes tumor progression and immune escape by modulating the farnesol X receptor in hepatocellular carcinoma.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Norcholic Acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Norcholic Acid (Nor Cholic Acid) is a bile acid that promotes tumor progression and immune escape by modulating the farnesol X receptor in hepatocellular carcinoma.
  • Description
    Norcholic acid is a normal minorbile C23 bile acid having four side chain and exsits in human urine and meconium. Norcholic acid can become prominent under certain pathological conditions. Norcholic acid is efficiently absorbed from intestine and quickly excreted into the bile but not into urine.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Wistar rats (100~150g)Dosage:6.4 g/L Administration:P.o.Result:Shows that averaging 40 % of the administered radioactivity was recovered from the feces during the first 24 hours.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    60696-62-0
  • Formula Weight
    394.54
  • Molecular Formula
    C23H38O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (253.46 mM; Ultrasonic )
  • SMILES
    [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)[C@H](C)CC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Nakatomi F, et al. Intestinal absorption and metabolism of norcholic acid in rats. J Pharmacobiodyn. 1985;8(7):557-563.?
molnova catalog
related products
  • 5-ROX, SE

    5-ROX, SE is a labeling reagen used in the preparation of charge-modified dye-labeled Dideoxynucleotide Triphosphates (ddNTP) to "direct-load" DNA sequencing.

  • DFHO

    DFHO is a Corn homologous ligand that fluoresces yellow upon excitation and is used to image RNA in living cells.

  • 4-Methoxycinnamyl al...

    4-Methoxycinnamyl alcohol showed toxicity to MCF-7, HeLa and DU145 cancer cell lines with IC50 values of 14.24, 7.82 and 22.10 μg/mL, respectively.